Multifocal Gastrointestinal Melanoma

Multifocal Malignant Melanoma of Female Ge-nital Tract

A 75-year–old patient was referred with vaginal bleeding. Her physical exam showed two flat dark plaques on the posterior fourchette, mostly on left lateral side of the vulva. A black soft mucosal nodule was present on the left lateral side of upper vagina, and a polypoid ulcerative cervical lesion extended into the right parametrium. Cervical and vaginal biopsies were in favor of malignant mel...

Multifocal amelanotic conjunctival melanoma

Clinical and histopathological features of four cases of multifocal amelanotic malignant melanoma of the conjunctiva in association with 'acquired melanosis sine pigmento' are reported. The absence ofconjunctival pigmentation in this extremely rare combination of lesions prevented early diagnosis and clinical monitoring. As a result orbital exenteration was required in three cases. This multice...

Multifocal angiosarcoma of the gastrointestinal tract.

Multifocal melanoma of the glans penis.

Malignant melanomas of the penis and urethra are rare.1–7 These lesions typically appear in an older age group.1–3,5–8 Presentation is usually late,1,6 with thick primary lesions9 and a high incidence of regional metastatic disease.1,5,8 Little is known about risk factors for or the pathogenesis of this disease. Furthermore, there is lack of consensus as to the extent of treatment that is indic...

Multifocal Malignant Melanoma of Female Genital Tract

A 75-year–old patient was referred with vaginal bleeding. Her physical exam showed two flat dark plaques on the posterior fourchette, mostly on left lateral side of the vulva. A black soft mucosal nodule was present on the left lateral side of upper vagina, and a polypoid ulcerative cervical lesion extended into the right parametrium. Cervical and vaginal biopsies were in favor of malignant mel...